- (Apr 2019) Multi-institutional TSA-amplified Multiplexed Immunofluorescence
- (Apr 2019) Quantifying tumor heterogeneity and mapping complex immune cell interactions with high-throughput, 7-color multispectral slide scans
- (Jan 2019) Primary Antibodies and Opal Pairings for Multiplex IHC
- (Oct 2018) Phenoptics 2.0 Advances Multiplex Fluorescence Immunohistochemistry: 9-color Imaging; Whole Slide Multispectral
- (Oct 2018) Phenoptics 2.0 Workflows and Applications for Whole Slide Multispectral Imaging
Data
Publications
- (Jul 2019) Comparison of Biomarker Modalities for Predicting Response to PD-1/PD-L1 Checkpoint Blockade
- (Mar 2019) Multiplexed Immunohistochemistry for Molecular and Immune Profiling in Lung Cancer—Just About Ready for Prime-Time?
- (Sep 2019) Phenotypic Plasticity of Fibroblasts during Mammary Carcinoma Development
- (Feb 2019) A Human iPSC-derived 3D platform using primary brain cancer cells to study drug development and personalized medicine
- (May 2016) Multispectral Imaging of T and B Cells in Murine Spleen and Tumor
- (Sep 2015) Nivolumab and Urelumab Enhance Antitumor Activity of Human T Lymphocytes Engrafted in Rag2-/-IL2Rγnull Immunodeficient Mice
- (Aug 2015) Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo
- (Feb 2017) Distinct patterns of infiltrating CD8+ T cells in HPV+ and CD68 macrophages in HPV- oropharyngeal squamous cell carcinomas are associated with better clinical outcome but PD-L1 expression is not prognostic
- (2011) Reversal of glial and neurovascular markers of unhealthy brain aging by exercise in middle-aged female mice
- (2012) Spectral imaging in preclinical research and clinical pathology
Pro Tips
- Garbage in, garbage out: A critical evaluation of strategies used for validation of immunohistochemical biomarkers
- Guided Tour of a 7 Color MOTIF™ Digital Slide (video)
- IHC Guidebook: Sixth Edition from Dako
- Next Generation Cancer Treatment: Patient Stratification with Immuno-Oncology (video)
- Opal Bench Tips (video)
- Value of Autofluorescence Isolation Using MOTiF™ Whole Slide Multispectral Technology (video)
- Vectra Polaris: Under the Hood (video)
- Whole Slide Multiplex Tissue Analysis with Vectra Polaris (video)